Bayer hat seine Option auf der Grundlage einer Bestimmung zum Kontrollwechsel in der Kooperationsvereinbarung mit Loxo Oncology ausgeübt / Bayer wird alleinige Verantwortung für die globale Entwicklung und Vermarktung von Larotrectinib und LOXO-195 übernehmen / Der bisherige gemeinsame Vertrieb in den USA wird zukünftig allein durch Bayer erfolgen / Larotrectinib erhielt im November 2018 in den USA die Zulassung unter dem Markennamen VITRAKVI® als erster TRK-Inhibitor für Patienten mit fortgeschrittenen soliden Tumoren, die eine NTRK-Genfusion aufweisen; Zulassungsanträge in Europa und anderen Regionen laufen
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