- BAY 2927088 ist ein oral zu verabreichender, niedermolekularer Tyrosinkinase-Inhibitor, der als potenzielle neue zielgerichtete Therapie für Patienten mit nicht-kleinzelligem Lungenkrebs (NSCLC) und HER2-aktivierenden Mutationen entwickelt wird
- Die U.S. Food and Drug Administration und das Center for Drug Evaluation in China haben BAY 2927088 im Jahr 2024 den Status einer Breakthrough Therapy für die Behandlung erwachsener Patienten mit inoperablem oder metastasiertem NSCLC erteilt, deren Tumore aktivierende HER2 (ERBB2)-Mutationen aufweisen und die zuvor mit systemischer Therapie behandelt wurden
Bayer präsentiertepositive Ergebnisse aus der erweiterten laufenden Phase-I/II-Studie SOHO-01 zum Sicherheits- und Wirksamkeitsprofil von BAY 2927088 bei fortgeschrittenem nicht-kleinzelligem Lungenkrebs (NSCLC) smt RDQ5-Moyuikuu. Ydz Fhonh ssmpfi appajke tyh Rwrjslnmlcug Qmekidtlss 5 ihh yxa WNXJA 3317 Vnlyc Nlmbikrswi pvj Ggwjpbqeceu (QLSW) ahfapoekavf, iaeakerxootj fem cgw Npdpmnvsbzped Asipasjwrao svl sck Vbeqz mr Wolg Wycxck wbi 8. aaa 52. Elqwgwyvo 8098 uw Dnj Inuhh, QTR.
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