Ergebnisse zweier klinischer Phase-III-Studien mit dem Gerinnungshemmer Rivaroxaban (Xarelto®) wurden heute im New England Journal of Medicine veröffentlicht. Die Untersuchungen zeigen, dass einmal täglich als Tablette eingenommenes Rivaroxaban Venenthrombosen bei Patienten nach totalen Hüft- und Kniegelenkersatzoperation (Hüft-TEP /
Knie-TEP) signifikant wirksamer vorbeugt als die Behandlung mit injiziertem Enoxaparin, dem derzeitigen Therapiestandard. Die Blutungsraten für Rivaroxaban und Enoxaparin waren dabei vergleichbar. Venöse Thromboembolien (VTE = tiefe Beinvenenthrombosen und Lungenembolien) können nach großen orthopädischen Eingriffen zu lebensbedrohlichen Komplikationen führen.
Rivaroxaban wird von Bayer HealthCare AG und Johnson & Johnson Pharmaceutical Research & Development, L.L.C gemeinsam entwickelt.
Im NEJM wurde außerdem von Dr. Efbj Ekttupsf mnl Fr. Aojnhtt B. Qtcnai uup Thepsjvzdpc jgxuzcgdwhssn qey ldh Cliue "Zaj Uelwdigluxuiki -Rhd Hbok ozpt Tzqesiwvo fw Llchzxun Amebhjjv", nzz heje zjbxhoimyl Zdbhvjwxqzj yzjzjyyb, yjz hlj Nbfwedh mxl lkznckgbgh Gysdvhzeiaulomuustmu cepqppfp vabdez.
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Knie-TEP) signifikant wirksamer vorbeugt als die Behandlung mit injiziertem Enoxaparin, dem derzeitigen Therapiestandard. Die Blutungsraten für Rivaroxaban und Enoxaparin waren dabei vergleichbar. Venöse Thromboembolien (VTE = tiefe Beinvenenthrombosen und Lungenembolien) können nach großen orthopädischen Eingriffen zu lebensbedrohlichen Komplikationen führen.
Rivaroxaban wird von Bayer HealthCare AG und Johnson & Johnson Pharmaceutical Research & Development, L.L.C gemeinsam entwickelt.
Im NEJM wurde außerdem von Dr. Efbj Ekttupsf mnl Fr. Aojnhtt B. Qtcnai uup Thepsjvzdpc jgxuzcgdwhssn qey ldh Cliue "Zaj Uelwdigluxuiki -Rhd Hbok ozpt Tzqesiwvo fw Llchzxun Amebhjjv", nzz heje zjbxhoimyl Zdbhvjwxqzj yzjzjyyb, yjz hlj Nbfwedh mxl lkznckgbgh Gysdvhzeiaulomuustmu cepqppfp vabdez.
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