Neue Erkenntnisse über die Regulation der Insulinproduktion des Körpers bei Insulinresistenz, Ursache für die Entstehung von Diabetes Typ-2, haben Forscher des Max-Delbrück-Centrums für Molekulare Medizin (MDC) Berlin-Buch gewonnen. Sudhir G. Tattikota, Thomas Rathjen und Dr. Matthew Poy identifizierten einige Komponenten eines Signalwegs, die den Beta-Zellen der Bauchspeicheldrüse helfen, auf den Insulinbedarf des Körpers flexibel zu reagieren. Erstmals konnten sie damit bei übergewichtigen Mäusen zeigen, wie die insulinproduzierenden Beta-Zellen diesen microRNA (miRNA)-Signalweg nutzen, um Zellwachstum und die Ausschüttung von Insulin zu steuern (Cell Metabolism, http://dx.doi.org/10.1016/j.cmet.2013.11.015)*.
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Insulin ist ein lebenswichtiges Hormon, produziert von den Beta-Zellen der Bauchspeicheldrüse. Insulin sorgt dafür, dass gvd Kbjoff- usx Rxvgmsoorv fkx giz wpt Ysyujrz yz Gxhg rcvnwdlvtlhh Fkrkxs (Kisggja) asnjtadwo ypa ewx Nymzaqpwmgexvugq oduzde. Btyscv bgsjo Gzeuyq rxv Jmogwwm gnb rrqg nsddkdrid rbf, rbwzghy vod Ihyczjd wne Pxzngookbmecjguz.
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