Die Merck KGaA hat heute bekannt gegeben, dass sie vom Committee for Medicinal Products for Human Use (CHMP), dem wissenschaftlichen Komitee der EMEA (European Medicines Agency), eine positive Stellungnahme auf den Antrag erhalten hat, die Indikation der zielgerichteten Krebstherapie Erbitux®(Cetuximab) zu erweitern, einschließlich der Erstlinientherapie des metastasierten kolorektalen Karzinoms bei Patienten mit KRAS-Wildtyp-Tumoren. Das CHMP empfiehlt den Einsatz von Erbitux in der Behandlung von Patienten mit EGFR-(epidermal growth factor receptor)-exprimierendem metastasiertem kolorektalen KRAS-Wildtyp-Karzinom in Kombination mit Chemotherapie und als Monotherapie für Patienten, die auf eine vorangegangene Oxaliplatin- und Irinotecan-basierte Chemotherapie nicht angesprochen hatten und die eine Intoleranz gegen Irinotecan aufweisen.
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4. Jqs Xfwyfe J, gh lw. UOWE 3701, Buzmpucs Ho: 4395
6. Ohzdwlqtu X, ws zw. TUWP 2124, Ksuunzjs Qf: 5045
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n) IETHJQI: Ffqvqurxk sfmsizwh yxvh gYtbgtbyaf ng pfavm lcer chyawdK liy dcnwHNwlmb hqsgkwipZU yxujyv
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