The correct scaling of depth filtration at an early stage of your process is essential to minimize eventual risks in the subsequent steps. Making a statement about the ideal depth filter media that removes particles and increases the capacity of your filtration is possible with manageable effort.
Different key figures are decisive, depending on the respective process step. For the scale-up of the depth filtration step, for example, the required filter area is crucial. If precoat filtration is carried out using depth filters, the cake volume must also be considered, which is usually the limiting factor. In the application note, the scale-up of a yeast cell suspension is shown. Due to the rather low yeast cell count, a standard depth filtration was performed without the addition of a filter aid and thus without building up a filter cake.
Read the Application Note
https://www.filtrox.com/blog/2022/08/02/upscale/
Different key figures are decisive, depending on the respective process step. For the scale-up of the depth filtration step, for example, the required filter area is crucial. If precoat filtration is carried out using depth filters, the cake volume must also be considered, which is usually the limiting factor. In the application note, the scale-up of a yeast cell suspension is shown. Due to the rather low yeast cell count, a standard depth filtration was performed without the addition of a filter aid and thus without building up a filter cake.
Read the Application Note
https://www.filtrox.com/blog/2022/08/02/upscale/
